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Comparative Functional Analysis of 12 Mammalian IFN-λ4 Orthologs

IFN-λ4 is a novel type-III interferon with strong clinical significance in humans. Only a subset of individuals—up to 10% of Asians, 50% of Europeans, and 90% of Africans—carry the ΔG allele of a genetic variant rs368234815-TT/ΔG and are genetically able to produce IFN-λ4 protein. Carriers of the ΔG...

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書目詳細資料
發表在:J Interferon Cytokine Res
Main Authors: Paquin, Ashley, Onabajo, Olusegun O., Tang, Wei, Prokunina-Olsson, Ludmila
格式: Artigo
語言:Inglês
出版: Mary Ann Liebert, Inc. 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722605/
https://ncbi.nlm.nih.gov/pubmed/26308395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2015.0096
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