載入...

Increasing the Receptor Tyrosine Kinase EphB2 Prevents Amyloid-β-induced Depletion of Cell Surface Glutamate Receptors by a Mechanism That Requires the PDZ-binding Motif of EphB2 and Neuronal Activity

Diverse lines of evidence suggest that amyloid-β (Aβ) peptides causally contribute to the pathogenesis of Alzheimer disease (AD), the most frequent neurodegenerative disorder. However, the mechanisms by which Aβ impairs neuronal functions remain to be fully elucidated. Previous studies showed that s...

全面介紹

Na minha lista:
書目詳細資料
發表在:J Biol Chem
Main Authors: Miyamoto, Takashi, Kim, Daniel, Knox, Joseph A., Johnson, Erik, Mucke, Lennart
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2016
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722453/
https://ncbi.nlm.nih.gov/pubmed/26589795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.666529
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!