The Eph Tyrosine Kinase Receptors EphB2 and EphA2 Are Novel Proteolytic Substrates of Tissue Factor/Coagulation Factor VIIa

Tissue factor (TF) binds the serine protease factor VIIa (FVIIa) to form a proteolytically active complex that can trigger coagulation or activate cell signaling. Here we addressed the involvement of tyrosine kinase receptors (RTKs) in TF/FVIIa signaling by antibody array analysis and subsequently f...

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Vydáno v:J Biol Chem
Hlavní autoři: Eriksson, Oskar, Ramström, Margareta, Hörnaeus, Katarina, Bergquist, Jonas, Mokhtari, Dariush, Siegbahn, Agneta
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Molecular Bases of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239594/
https://ncbi.nlm.nih.gov/pubmed/25281742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.599332
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