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Interleukin 1β Regulation of the System x(c)(−) Substrate-specific Subunit, xCT, in Primary Mouse Astrocytes Involves the RNA-binding Protein HuR
System x(c)(−) is a heteromeric amino acid cystine/glutamate antiporter that is constitutively expressed by cells of the CNS, where it functions in the maintenance of intracellular glutathione and extracellular glutamate levels. We recently determined that the cytokine, IL-1β, increases the activity...
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| I publikationen: | J Biol Chem |
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| Huvudupphovsmän: | , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Biochemistry and Molecular Biology
2016
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4722447/ https://ncbi.nlm.nih.gov/pubmed/26601945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.697821 |
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