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Selective Mitochondrial Uptake of MKT-077 Can Suppress Medullary Thyroid Carcinoma Cell Survival In Vitro and In Vivo

BACKGROUND: Medullary thyroid carcinoma (MTC) is a neuroendocrine tumor mainly caused by mutations in the rearranged during transfection (RET) proto-oncogene. Not all patients with progressive MTC respond to current therapy inhibiting RET, demanding additional therapeutic strategies. We recently dem...

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Detalhes bibliográficos
Publicado no:Endocrinol Metab (Seoul)
Main Authors: Starenki, Dmytro, Park, Jong-In
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Endocrine Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722416/
https://ncbi.nlm.nih.gov/pubmed/26485469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3803/EnM.2015.30.4.593
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