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Brief low [Mg(2+)](o)-induced Ca(2+) spikes inhibit subsequent prolonged exposure-induced excitotoxicity in cultured rat hippocampal neurons
Reducing [Mg(2+)](o) to 0.1 mM can evoke repetitive [Ca(2+)](i) spikes and seizure activity, which induces neuronal cell death in a process called excitotoxicity. We examined the issue of whether cultured rat hippocampal neurons preconditioned by a brief exposure to 0.1 mM [Mg(2+)](o) are rendered r...
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| Publicado no: | Korean J Physiol Pharmacol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Korean Physiological Society and The Korean Society of Pharmacology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4722183/ https://ncbi.nlm.nih.gov/pubmed/26807029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2016.20.1.101 |
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