Proteasome inhibition after burn injury

OBJECTIVE: To assess the effects of proteasome inhibition on the development of burn-induced hypermetabolism. METHODS: Rats underwent 30–40% TBSA scald burn or sham injury. The proteasome inhibitor bortezomib (0.1 mg/kg) or vehicle (n=10) was administered i.p. 3×weekly starting at 2h (Early-Bortezom...

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Bibliografiske detaljer
Udgivet i:J Burn Care Res
Main Authors: Vana, P. Geoff, LaPorte, Heather M., Wong, Yee M., Kennedy, Richard H., Gamelli, Richard L., Majetschak, Matthias
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4721944/
https://ncbi.nlm.nih.gov/pubmed/26204383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/BCR.0000000000000280
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