Scalable Production of a Multifunctional Protein (TSG-6) That Aggregates with Itself and the CHO Cells That Synthesize It

TNF-α stimulated gene/protein 6 (TNFAIP6/TSG-6) is a multifunctional protein that has a number of potential therapeutic applications. Experiments and clinical trials with TSG-6, however, have been limited by the technical difficulties of producing the recombinant protein. We prepared stable clones o...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Kim, Dong-Ki, Choi, Hosoon, Nishida, Hidetaka, Oh, Joo Youn, Gregory, Carl, Lee, Ryang Hwa, Yu, Ji Min, Watanabe, Jun, An, Su Yeon, Bartosh, Thomas J., Prockop, Darwin J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4721919/
https://ncbi.nlm.nih.gov/pubmed/26793973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147553
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