Stress-Induced Anxiety- and Depressive-Like Phenotype Associated with Transient Reduction in Neurogenesis in Adult Nestin-CreER(T2)/Diphtheria Toxin Fragment A Transgenic Mice

Depression and anxiety involve hippocampal dysfunction, but the specific relationship between these mood disorders and adult hippocampal dentate gyrus neurogenesis remains unclear. In both humans with MDD and rodent models of depression, administration of antidepressants increases DG progenitor and...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yun, Sanghee, Donovan, Michael H., Ross, Michele N., Richardson, Devon R., Reister, Robin, Farnbauch, Laure A., Fischer, Stephanie J., Riethmacher, Dieter, Gershenfeld, Howard K., Lagace, Diane C., Eisch, Amelia J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4721672/
https://ncbi.nlm.nih.gov/pubmed/26795203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147256
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