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Three-dimensional structure of a heteroclitic antigen-antibody cross-reaction complex.

Although antibodies are highly specific, cross-reactions are frequently observed. To understand the molecular basis of this phenomenon, we studied the anti-hen egg lysozyme (HEL) monoclonal antibody (mAb) D11.15, which cross-reacts with several avian lysozymes, in some cases with a higher affinity (...

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Hlavní autoři: Chitarra, V, Alzari, P M, Bentley, G A, Bhat, T N, Eiselé, J L, Houdusse, A, Lescar, J, Souchon, H, Poljak, R J
Médium: Artigo
Jazyk:Inglês
Vydáno: 1993
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC47212/
https://ncbi.nlm.nih.gov/pubmed/8356074
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