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Staphylococcal Enterotoxin B (SEB) Induces Memory CD4 T Cell Anergy in vivo and Impairs Recall Immunity to Unrelated Antigens

INTRODUCTION: Naïve and memory T cells can utilize unique regulatory pathways to promote protection but prevent self-reactivity. A bacterial superantigen SEB exploits unique TCR proximal signaling processes in memory CD4 T cells to induce clonal anergy. The aim of this study was to determine if SEB...

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Detalhes bibliográficos
Publicado no:J Clin Cell Immunol
Main Authors: Janik, David K, Lee, William T
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720977/
https://ncbi.nlm.nih.gov/pubmed/26807307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-9899.1000346
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