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Superantigen-induced CD4 Memory T Cell Anergy. I. Staphylococcal Enterotoxin B Induces Fyn-mediated Negative Signaling()

Memory CD4 T cells must provide robust protection for an organism while still maintaining self-tolerance. Superantigens reveal a memory cell-specific regulatory pathway, by which signaling through the TCR can lead to clonal tolerance (anergy). Here we show that the src kinase Fyn is a critical regul...

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Bibliografische gegevens
Hoofdauteurs: Watson, Andrew R. O., Janik, David K., Lee, William T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374044/
https://ncbi.nlm.nih.gov/pubmed/22386537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2012.02.003
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