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Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10

Numerous studies of the anti-HIV-1 envelope glycoprotein 41 (gp41) broadly neutralizing antibody 4E10 suggest that 4E10 also interacts with membrane lipids, but the antibody regions contacting lipids and its orientation with respect to the viral membrane are unknown. Vaccine immunogens capable of re...

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Dades bibliogràfiques
Publicat a:Immunity
Autors principals: Irimia, Adriana, Sarkar, Anita, Stanfield, Robyn L., Wilson, Ian A.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720917/
https://ncbi.nlm.nih.gov/pubmed/26777395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.12.001
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