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Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10
Numerous studies of the anti-HIV-1 envelope glycoprotein 41 (gp41) broadly neutralizing antibody 4E10 suggest that 4E10 also interacts with membrane lipids, but the antibody regions contacting lipids and its orientation with respect to the viral membrane are unknown. Vaccine immunogens capable of re...
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Publicat a: | Immunity |
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Autors principals: | , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
2016
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4720917/ https://ncbi.nlm.nih.gov/pubmed/26777395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.12.001 |
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