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A Fluorescent Analog of Batimastat Enables Imaging of α-Secretase in Living Cells
The ADAM family of metalloproteases cleave a diverse range of transmembrane substrates, resulting in the release of their soluble ectodomains. This process of protein shedding, termed α-secretase processing, is involved in many facets of both normal and disease related cellular function. While the p...
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| Published in: | ACS Chem Neurosci |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4720558/ https://ncbi.nlm.nih.gov/pubmed/26559179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.5b00283 |
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