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Understanding TRPV1 activation by ligands: Insights from the binding modes of capsaicin and resiniferatoxin
The transient receptor potential cation channel subfamily V member 1 (TRPV1) or vanilloid receptor 1 is a nonselective cation channel that is involved in the detection and transduction of nociceptive stimuli. Inflammation and nerve damage result in the up-regulation of TRPV1 transcription, and, ther...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4720335/ https://ncbi.nlm.nih.gov/pubmed/26719417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1517288113 |
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