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Short Telomeres in Key Tissues Initiate Local and Systemic Aging in Zebrafish
Telomeres shorten with each cell division and telomere dysfunction is a recognized hallmark of aging. Tissue proliferation is expected to dictate the rate at which telomeres shorten. We set out to test whether proliferative tissues age faster than non-proliferative due to telomere shortening during...
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| Udgivet i: | PLoS Genet |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4720274/ https://ncbi.nlm.nih.gov/pubmed/26789415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005798 |
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