Short Telomeres in Key Tissues Initiate Local and Systemic Aging in Zebrafish

Telomeres shorten with each cell division and telomere dysfunction is a recognized hallmark of aging. Tissue proliferation is expected to dictate the rate at which telomeres shorten. We set out to test whether proliferative tissues age faster than non-proliferative due to telomere shortening during...

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Bibliografiska uppgifter
I publikationen:PLoS Genet
Huvudupphovsmän: Carneiro, Madalena C., Henriques, Catarina M., Nabais, Joana, Ferreira, Tânia, Carvalho, Tânia, Ferreira, Miguel Godinho
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720274/
https://ncbi.nlm.nih.gov/pubmed/26789415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005798
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