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Multidimensional Separation Using HILIC and SCX Pre-fractionation for RP LC-MS/MS Platform with Automated Exclusion List-based MS Data Acquisition with Increased Protein Quantification

Liquid chromatography–mass spectrometry (LC-MS) based proteomics is one of the most widely used analytical platforms for global protein discovery and quantification. One of the challenges is the difficulty of identifying low abundance biomarker proteins from limited biological samples. Extensive fra...

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Dettagli Bibliografici
Pubblicato in:J Proteomics Bioinform
Autori principali: Zhou, Yu, Meng, Zhen, Edman-Woolcott, Maria, Hamm-Alvarez, Sarah F, Zandi, Ebrahim
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720167/
https://ncbi.nlm.nih.gov/pubmed/26807013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/jpb.1000378
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