Antitumor Activity of HM781-36B, alone or in Combination with Chemotherapeutic Agents, in Colorectal Cancer Cells

PURPOSE: HM781-36B is a novel and irreversible pan-human epidermal growth factor receptor (HER) inhibitor with TEC cytoplasmic kinase inhibition. The aim of this study is to evaluate the antitumor activity and mechanism of action for HM781-36B in CRC cell lines. MATERIALS AND METHODS: The CRC cell l...

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Vydáno v:Cancer Res Treat
Hlavní autoři: Kang, Mi Hyun, Moon, Sung Ung, Sung, Ji Hea, Kim, Jin Won, Lee, Keun Wook, Lee, Hye Seung, Lee, Jong Seok, Kim, Jee Hyun
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Cancer Association 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720083/
https://ncbi.nlm.nih.gov/pubmed/25761479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2014.260
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