A Comprehensive RNA Sequencing Analysis of the Adeno-Associated Virus (AAV) Type 2 Transcriptome Reveals Novel AAV Transcripts, Splice Variants, and Derived Proteins

Adeno-associated virus (AAV) is recognized for its bipartite life cycle with productive replication dependent on coinfection with adenovirus (Ad) and AAV latency being established in the absence of a helper virus. The shift from latent to Ad-dependent AAV replication is mostly regulated at the trans...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Stutika, Catrin, Gogol-Döring, Andreas, Botschen, Laura, Mietzsch, Mario, Weger, Stefan, Feldkamp, Mirjam, Chen, Wei, Heilbronn, Regine
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Genome Replication and Regulation of Viral Gene Expression
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719636/
https://ncbi.nlm.nih.gov/pubmed/26559843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02750-15
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