Knockdown of Autophagy Inhibits Infectious Hepatitis C Virus Release by the Exosomal Pathway

Hepatitis C virus (HCV) is a major cause of chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma in humans. We showed previously that HCV induces autophagy for viral persistence by preventing the innate immune response. Knockdown of autophagy reduces extracellular HCV release, although t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Virol
Prif Awduron: Shrivastava, Shubham, Devhare, Pradip, Sujijantarat, Nanthiya, Steele, Robert, Kwon, Young-Chan, Ray, Ranjit, Ray, Ratna B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2016
Pynciau:
Virus-Cell Interactions
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719613/
https://ncbi.nlm.nih.gov/pubmed/26581990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02383-15
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