Knockdown of Autophagy Inhibits Infectious Hepatitis C Virus Release by the Exosomal Pathway

Hepatitis C virus (HCV) is a major cause of chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma in humans. We showed previously that HCV induces autophagy for viral persistence by preventing the innate immune response. Knockdown of autophagy reduces extracellular HCV release, although t...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Shrivastava, Shubham, Devhare, Pradip, Sujijantarat, Nanthiya, Steele, Robert, Kwon, Young-Chan, Ray, Ranjit, Ray, Ratna B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
Soggetti:
Virus-Cell Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719613/
https://ncbi.nlm.nih.gov/pubmed/26581990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02383-15
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