Possible role of Krüppel-like factor 5 in the remodeling of small airways and pulmonary vessels in chronic obstructive pulmonary disease

BACKGROUND: Small airway remodeling is an important cause of the airflow limitation in chronic obstructive pulmonary disease (COPD). A large population of patients with COPD also have pulmonary hypertension. Krüppel-like factor 5 (KLF5) is a zinc-finger transcription factor that contributes to tissu...

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Udgivet i:Respir Res
Main Authors: Abe, Kyoko, Sugiura, Hisatoshi, Hashimoto, Yuichiro, Ichikawa, Tomohiro, Koarai, Akira, Yamada, Mitsuhiro, Numakura, Tadahisa, Onodera, Katsuhiro, Tanaka, Rie, Sato, Kei, Yanagisawa, Satoru, Okazaki, Tatsuma, Tamada, Tsutomu, Kikuchi, Toshiaki, Ichinose, Masakazu
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719583/
https://ncbi.nlm.nih.gov/pubmed/26792671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0322-y
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