Filamin A Expression Negatively Regulates Sphingosine-1-Phosphate-Induced NF-κB Activation in Melanoma Cells by Inhibition of Akt Signaling

Sphingosine-1-phosphate (S1P) is a bioactive lipid mediator that regulates many processes in inflammation and cancer. S1P is a ligand for five G-protein-coupled receptors, S1PR1 to -5, and also has important intracellular actions. Previously, we showed that intracellular S1P is involved in tumor nec...

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Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Campos, Ludmila S., Rodriguez, Yamila I., Leopoldino, Andreia M., Hait, Nitai C., Lopez Bergami, Pablo, Castro, Melina G., Sanchez, Emilse S., Maceyka, Michael, Spiegel, Sarah, Alvarez, Sergio E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719300/
https://ncbi.nlm.nih.gov/pubmed/26552704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00554-15
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