Grafted Human iPS Cell-Derived Oligodendrocyte Precursor Cells Contribute to Robust Remyelination of Demyelinated Axons after Spinal Cord Injury

Murine- and human-induced pluripotent stem cell-derived neural stem/progenitor cells (iPSC-NS/PCs) promote functional recovery following transplantation into the injured spinal cord in rodents and primates. Although remyelination of spared demyelinated axons is a critical mechanism in the regenerati...

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Pubblicato in:Stem Cell Reports
Autori principali: Kawabata, Soya, Takano, Morito, Numasawa-Kuroiwa, Yuko, Itakura, Go, Kobayashi, Yoshiomi, Nishiyama, Yuichiro, Sugai, Keiko, Nishimura, Soraya, Iwai, Hiroki, Isoda, Miho, Shibata, Shinsuke, Kohyama, Jun, Iwanami, Akio, Toyama, Yoshiaki, Matsumoto, Morio, Nakamura, Masaya, Okano, Hideyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2015
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Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719132/
https://ncbi.nlm.nih.gov/pubmed/26724902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.11.013
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