Bile acids regulate intestinal cell proliferation by modulating EGFR and FXR signaling

Bile acids (BAs) are synthesized in the liver and secreted into the intestine. In the lumen, enteric bacteria metabolize BAs from conjugated, primary forms into more toxic unconjugated, secondary metabolites. Secondary BAs can be injurious to the intestine and may contribute to disease. The epiderma...

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Vydáno v:Am J Physiol Gastrointest Liver Physiol
Hlavní autoři: Dossa, Avafia Y., Escobar, Oswaldo, Golden, Jamie, Frey, Mark R., Ford, Henri R., Gayer, Christopher P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2015
Témata:
Hormones, Neurotransmitters, Growth Factors, Receptors, and Signaling
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719061/
https://ncbi.nlm.nih.gov/pubmed/26608185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00065.2015
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