ATP promotes cell survival via regulation of cytosolic [Ca(2+)] and Bcl-2/Bax ratio in lung cancer cells

Adenosine triphosphate (ATP) is a ubiquitous extracellular messenger elevated in the tumor microenvironment. ATP regulates cell functions by acting on purinergic receptors (P2X and P2Y) and activating a series of intracellular signaling pathways. We examined ATP-induced Ca(2+) signaling and its effe...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Song, Shanshan, Jacobson, Krista N., McDermott, Kimberly M., Reddy, Sekhar P., Cress, Anne E., Tang, Haiyang, Dudek, Steven M., Black, Stephen M., Garcia, Joe G. N., Makino, Ayako, Yuan, Jason X.-J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
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Call for Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719033/
https://ncbi.nlm.nih.gov/pubmed/26491047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00092.2015
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