Deleterious c-Cbl Exon Skipping Contributes to Human Glioma()()

c-Cbl, a RING-type ubiquitin E3 ligase, downregulates various receptor tyrosine kinases (e.g., epidermal growth factor receptor (EGFR)), leading to inhibition of cell proliferation. Moreover, patients with myeloid neoplasm frequently harbor c-Cbl mutations, implicating the role of c-Cbl as a tumor s...

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Publicado en:Neoplasia
Autores principales: Seong, Min Woo, Ka, Seung Hyeun, Park, Ji Ho, Park, Jong Ho, Yoo, Hee Min, Yang, Seung Wook, Park, Jung Mi, Park, Dongeun, Lee, Soon Tae, Seol, Jae Hong, Chung, Chin Ha
Formato: Artigo
Lenguaje:Inglês
Publicado: Neoplasia Press 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719003/
https://ncbi.nlm.nih.gov/pubmed/26152360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2015.06.003
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