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Deleterious c-Cbl Exon Skipping Contributes to Human Glioma()()
c-Cbl, a RING-type ubiquitin E3 ligase, downregulates various receptor tyrosine kinases (e.g., epidermal growth factor receptor (EGFR)), leading to inhibition of cell proliferation. Moreover, patients with myeloid neoplasm frequently harbor c-Cbl mutations, implicating the role of c-Cbl as a tumor s...
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| Udgivet i: | Neoplasia |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Neoplasia Press
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4719003/ https://ncbi.nlm.nih.gov/pubmed/26152360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2015.06.003 |
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