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Luteinizing hormone downregulation but not estrogen replacement improves ovariectomy-associated cognition and spine density loss independently of treatment onset timing

Age-related changes in reproductive hormone levels are a well-known risk factor for the development of cognitive dysfunction and dementia in women. We and others have shown an important contribution of gonadotropins in this process. Lowering serum gonadotropin levels is able to rescue cognitive func...

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Detalhes bibliográficos
Publicado no:Horm Behav
Main Authors: Blair, Jeffrey A., Palm, Russell, Chang, Jaewon, McGee, Henry, Zhu, Xiongwei, Wang, Xinglong, Smith, Gemma Casadesus
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718885/
https://ncbi.nlm.nih.gov/pubmed/26497249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yhbeh.2015.10.013
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