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Luteinizing hormone downregulation but not estrogen replacement improves ovariectomy-associated cognition and spine density loss independently of treatment onset timing

Age-related changes in reproductive hormone levels are a well-known risk factor for the development of cognitive dysfunction and dementia in women. We and others have shown an important contribution of gonadotropins in this process. Lowering serum gonadotropin levels is able to rescue cognitive func...

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Dettagli Bibliografici
Pubblicato in:Horm Behav
Autori principali: Blair, Jeffrey A., Palm, Russell, Chang, Jaewon, McGee, Henry, Zhu, Xiongwei, Wang, Xinglong, Smith, Gemma Casadesus
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718885/
https://ncbi.nlm.nih.gov/pubmed/26497249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yhbeh.2015.10.013
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