Downregulation of Serum Gonadotropins is as Effective as Estrogen Replacement at Improving Menopause-Associated Cognitive Deficits

While estrogen (E2) is thought to play an important role in age-related cognitive decline, neuronal plasticity, as well as the pathogenesis of Alzheimer disease (AD), the mechanisms by which estrogen exerts its beneficial effects are controversial. In this regard, declining levels of estrogen in wom...

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Detalhes bibliográficos
Main Authors: Bryan, Kathryn J., Mudd, Joseph C., Richardson, Sandy L., Chang, Jaewon, Lee, Hyoung-gon, Zhu, Xiongwei, Smith, Mark A., Casadesus, Gemma
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886127/
https://ncbi.nlm.nih.gov/pubmed/19943850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06502.x
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