The novel PPARγ modulator GED-0507-34 Levo ameliorates inflammation-driven intestinal fibrosis

BACKGROUND: Intestinal fibrosis is mainly associated with Crohn's disease (CD) and is defined as a progressive and excessive deposition of extracellular matrix (ECM) components. No specific anti-fibrotic therapies are available. In this study we evaluate the anti-fibrotic effect of GED, a novel...

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Vydáno v:Inflamm Bowel Dis
Hlavní autoři: Silvia, Speca, Christel, Rousseaux, Caroline, Dubuquoy, Florian, Rieder, Antonella, Vetuschi, Roberta, Sferra, Ilaria, Giusti, Benjamin, Bertin, Laurent, Dubuquoy, Eugenio, Gaudio, Pierre, Desreumaux, Giovanni, Latella
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718865/
https://ncbi.nlm.nih.gov/pubmed/26535766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0000000000000618
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