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Effects of the β1 Auxiliary Subunit on Modification of Rat Na(v)1.6 Sodium Channels Expressed in HEK293 Cells by the Pyrethroid Insecticides Tefluthrin and Deltamethrin

We expressed rat Na(v)1.6 sodium channels with or without the rat β1 subunit in human embryonic kidney (HEK293) cells and evaluated the effects of the pyrethroid insecticides tefluthrin and deltamethrin on whole-cell sodium currents. In assays with the Na(v)1.6 α subunit alone, both pyrethroids prol...

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Detalhes bibliográficos
Publicado no:Toxicol Appl Pharmacol
Main Authors: He, Bingjun, Soderlund, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718755/
https://ncbi.nlm.nih.gov/pubmed/26708501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2015.12.007
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