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Differential State-Dependent Modification of Rat Na(v)1.6 Sodium Channels Expressed in Human Embryonic Kidney (HEK293) Cells by the Pyrethroid Insecticides Tefluthrin and Deltamethrin

We expressed rat Na(v)1.6 sodium channels in combination with the rat β1 and β2 auxiliary subunits in human embryonic kidney (HEK293) cells and evaluated the effects of the pyrethroid insecticides tefluthrin and deltamethrin on expressed sodium currents using the whole-cell patch clamp technique. Bo...

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Bibliographic Details
Main Authors: He, Bingjun, Soderlund, David M.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226847/
https://ncbi.nlm.nih.gov/pubmed/21983428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2011.09.021
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