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Characterization of a Mannose-6-Phosphate Isomerase from Bacillus amyloliquefaciens and Its Application in Fructose-6-Phosphate Production

The BaM6PI gene encoding a mannose-6-phosphate isomerase (M6PI, EC 5.3.1.8) was cloned from Bacillus amyloliquefaciens DSM7 and overexpressed in Escherichia coli. The enzyme activity of BaM6PI was optimal at pH and temperature of 7.5 and 70°C, respectively, with a k(cat)/K(m) of 13,900 s(-1) mM(-1)...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sigdel, Sujan, Singh, Ranjitha, Kim, Tae-Su, Li, Jinglin, Kim, Sang-Yong, Kim, In-Won, Jung, Woo-Suk, Pan, Cheol-Ho, Kang, Yun Chan, Lee, Jung-Kul
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718643/
https://ncbi.nlm.nih.gov/pubmed/26171785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131585
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