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A Method for Extracting the Free Energy Surface and Conformational Dynamics of Fast-Folding Proteins from Single Molecule Photon Trajectories

[Image: see text] Single molecule fluorescence spectroscopy holds the promise of providing direct measurements of protein folding free energy landscapes and conformational motions. However, fulfilling this promise has been prevented by technical limitations, most notably, the difficulty in analyzing...

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Vydáno v:J Phys Chem B
Hlavní autoři: Ramanathan, Ravishankar, Muñoz, Victor
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2015
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718529/
https://ncbi.nlm.nih.gov/pubmed/25988351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.5b03176
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