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A Method for Extracting the Free Energy Surface and Conformational Dynamics of Fast-Folding Proteins from Single Molecule Photon Trajectories

[Image: see text] Single molecule fluorescence spectroscopy holds the promise of providing direct measurements of protein folding free energy landscapes and conformational motions. However, fulfilling this promise has been prevented by technical limitations, most notably, the difficulty in analyzing...

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Ramanathan, Ravishankar, Muñoz, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2015
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718529/
https://ncbi.nlm.nih.gov/pubmed/25988351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.5b03176
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