ALLOSTERIC REGULATION OF GPCR ACTIVITY BY PHOSPHOLIPIDS

Lipids are emerging as key regulators of membrane protein structure and activity. Such effects can either be attributed to modification in bilayer properties (thickness, curvature and surface tension) or to binding of specific lipids to the protein surface. For G Protein-Coupled Receptors (GPCRs), t...

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Udgivet i:Nat Chem Biol
Main Authors: Dawaliby, Rosie, Trubbia, Cataldo, Delporte, Cédric, Masureel, Matthieu, Van Antwerpen, Pierre, Kobilka, Brian K., Govaerts, Cédric
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718399/
https://ncbi.nlm.nih.gov/pubmed/26571351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1960
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