Loss of BAP1 Expression Occurs Frequently in Intrahepatic Cholangiocarcinoma

BRCA1-associated protein 1 (BAP1) is a deubiquitinating enzyme that functions as a tumor suppressor gene. Double hit BAP1 inactivation has been reported in a range of tumor types, including intrahepatic cholangiocarcinoma (ICC), sometimes in association with germline mutation. We performed immunohis...

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Detalhes bibliográficos
Publicado no:Medicine (Baltimore)
Main Authors: Andrici, Juliana, Goeppert, Benjamin, Sioson, Loretta, Clarkson, Adele, Renner, Marcus, Stenzinger, Albrecht, Tayao, Michael, Watson, Nicole, Farzin, Mahtab, Toon, Christopher W., Smith, Ross C., Mittal, Anubhav, Samra, Jaswinder S., Hugh, Thomas J., Chou, Angela, Lawlor, Rita T., Weichert, Wilko, Schirmacher, Peter, Sperandio, Nicola, Ruzzenente, Andrea, Scarpa, Aldo, Gill, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Health 2016
Assuntos:
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718285/
https://ncbi.nlm.nih.gov/pubmed/26765459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000002491
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