Loss of BAP1 Expression Occurs Frequently in Intrahepatic Cholangiocarcinoma

BRCA1-associated protein 1 (BAP1) is a deubiquitinating enzyme that functions as a tumor suppressor gene. Double hit BAP1 inactivation has been reported in a range of tumor types, including intrahepatic cholangiocarcinoma (ICC), sometimes in association with germline mutation. We performed immunohis...

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Veröffentlicht in:Medicine (Baltimore)
Hauptverfasser: Andrici, Juliana, Goeppert, Benjamin, Sioson, Loretta, Clarkson, Adele, Renner, Marcus, Stenzinger, Albrecht, Tayao, Michael, Watson, Nicole, Farzin, Mahtab, Toon, Christopher W., Smith, Ross C., Mittal, Anubhav, Samra, Jaswinder S., Hugh, Thomas J., Chou, Angela, Lawlor, Rita T., Weichert, Wilko, Schirmacher, Peter, Sperandio, Nicola, Ruzzenente, Andrea, Scarpa, Aldo, Gill, Anthony J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wolters Kluwer Health 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718285/
https://ncbi.nlm.nih.gov/pubmed/26765459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000002491
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