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A novel protocol for the one-pot borylation/Suzuki reaction provides easy access to hinge-binding groups for kinase inhibitors

The one-pot borylation/Suzuki reaction is a very efficient means of accessing cross-coupling products of two aryl-halide partners that generally requires the use of specific catalysts or ligands and/or relatively long reaction times. This new microwave-assisted method provides a quick one-pot boryla...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Hooper, A., Zambon, A., Springer, C. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718143/
https://ncbi.nlm.nih.gov/pubmed/26620576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5ob01915j
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