Random mutagenesis of yeast 25S rRNA identify bases critical for 60S subunit structural integrity and function

In yeast Saccharomyces cerevisiae, 25S rRNA makes up the major mass and shape of the 60S ribosomal subunit. During translation initiation, the 60S subunit joins the 40S initiation complex, producing the 80S initiation complex. During elongation, the 60S subunit binds the CCA-ends of aminoacyl- and p...

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Bibliographic Details
Published in:Translation (Austin)
Main Authors: Nemoto, Naoki, Udagawa, Tsuyoshi, Chowdhury, Wasimul, Kitabatake, Makoto, Shin, Byung-shik, Hiraishi, Hiroyuki, Wang, Suzhi, Singh, Chingakham Ranjit, Brown, Susan J., Ohno, Mutsuhito, Asano, Katsura
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2013
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718063/
https://ncbi.nlm.nih.gov/pubmed/26824023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trla.26402
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