Interaction between 25S rRNA A Loop and Eukaryotic Translation Initiation Factor 5B Promotes Subunit Joining and Ensures Stringent AUG Selection

In yeast, 25S rRNA makes up the major mass and shape of the 60S ribosomal subunit. During the last step of translation initiation, eukaryotic initiation factor 5B (eIF5B) promotes the 60S subunit joining with the 40S initiation complex (IC). Malfunctional 60S subunits produced by misfolding or mutat...

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Main Authors: Hiraishi, Hiroyuki, Shin, Byung-Sik, Udagawa, Tsuyoshi, Nemoto, Naoki, Chowdhury, Wasimul, Graham, Jymie, Cox, Christian, Reid, Megan, Brown, Susan J., Asano, Katsura
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753867/
https://ncbi.nlm.nih.gov/pubmed/23836883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00771-13
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