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Physical evidence supporting a ribosomal shunting mechanism of translation initiation for BACE1 mRNA

In Alzheimer disease, elevated levels of the BACE1 enzyme are correlated with increased production of amyloid peptides and disease pathology. The increase in BACE1 levels is post-transcriptional and may involve altered translation efficiency. Earlier studies have indicated that translation of BACE1...

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Vydáno v:Translation (Austin)
Hlavní autoři: Koh, Dora C., Edelman, Gerald M., Mauro, Vincent P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718059/
https://ncbi.nlm.nih.gov/pubmed/26824018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trla.24400
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