Maintenance of autoantibody production in pristane-induced murine lupus

BACKGROUND: Pristane-treated mice chronically produce high levels of anti-ribonucleoprotein/Smith (anti-Sm/RNP) and other lupus autoantibodies. The present study addressed how these autoantibody levels are maintained over time. METHODS: Lupus was induced in BALB/c mice using pristane. Naïve B cells,...

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Pubblicato in:Arthritis Res Ther
Autori principali: Han, Shuhong, Zhuang, Haoyang, Xu, Yuan, Lee, Pui, Li, Yi, Wilson, Joseph C., Vidal, Osvaldo, Choi, Hong Seok, Sun, Yu, Yang, Li-Jun, Reeves, Westley H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718029/
https://ncbi.nlm.nih.gov/pubmed/26717913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0886-9
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