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PTPRN2 and PLCβ1 promote metastatic breast cancer cell migration through PI(4,5)P(2)‐dependent actin remodeling
Altered abundance of phosphatidyl inositides (PIs) is a feature of cancer. Various PIs mark the identity of diverse membranes in normal and malignant cells. Phosphatidylinositol 4,5‐bisphosphate (PI(4,5)P(2)) resides predominantly in the plasma membrane, where it regulates cellular processes by recr...
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Publicado no: | EMBO J |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
John Wiley and Sons Inc.
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4717998/ https://ncbi.nlm.nih.gov/pubmed/26620550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201591973 |
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