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Prolonged silencing of diacylglycerol acyltransferase‐1 induces a dedifferentiated phenotype in human liver cells

Diacylglycerol acyltransferase‐1 (DGAT1), a key enzyme in triglyceride (TG) biogenesis, is highly associated with metabolic abnormalities, such as obesity and type 2 diabetes. However, the effects of DGAT1 silencing in the human liver have not been elucidated. To investigate the effects of DGAT1 sil...

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Bibliographic Details
Published in:J Cell Mol Med
Main Authors: Chang, Soyoung, Sung, Pil Soo, Lee, Jungsul, Park, Junseong, Shin, Eui‐Cheol, Choi, Chulhee
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717863/
https://ncbi.nlm.nih.gov/pubmed/26493024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12685
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