Hepatitis C Virus Entry Is Impaired by Claudin-1 Downregulation in Diacylglycerol Acyltransferase-1-Deficient Cells

Diacylglycerol acyltransferase-1 (DGAT1) is involved in the assembly of hepatitis C virus (HCV) by facilitating the trafficking of the HCV core protein to the lipid droplet. Here, we abrogated DGAT1 expression in Huh-7.5 cells by using either the transcription activator-like effector nuclease (TALEN...

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Detalhes bibliográficos
Main Authors: Sung, Pil Soo, Murayama, Asako, Kang, Wonseok, Kim, Myung-Sun, Yoon, Seung Kew, Fukasawa, Masayoshi, Kondoh, Masuo, Kim, Jin-Soo, Kim, Hyongbum, Kato, Takanobu, Shin, Eui-Cheol
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136266/
https://ncbi.nlm.nih.gov/pubmed/24899196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01428-14
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