The human rs1050286 polymorphism alters LOX‐1 expression through modifying miR‐24 binding

The up‐regulation of lectin‐like oxidized low‐density lipoprotein receptor‐1 (LOX‐1), encoded by the OLR1 gene, plays a fundamental role in the pathogenesis of atherosclerosis. Moreover, OLR1 polymorphisms were associated with increased susceptibility to acute myocardial infarction (AMI) and coronar...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Morini, Elena, Rizzacasa, Barbara, Pucci, Sabina, Polidoro, Chiara, Ferrè, Fabrizio, Caporossi, Daniela, Helmer Citterich, Manuela, Novelli, Giuseppe, Amati, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717858/
https://ncbi.nlm.nih.gov/pubmed/26542080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12716
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