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Computational methods for analysis and inference of kinase/inhibitor relationships

The central role of kinases in virtually all signal transduction networks is the driving motivation for the development of compounds modulating their activity. ATP-mimetic inhibitors are essential tools for elucidating signaling pathways and are emerging as promising therapeutic agents. However, off...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ferrè, Fabrizio, Palmeri, Antonio, Helmer-Citterich, Manuela
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075008/
https://ncbi.nlm.nih.gov/pubmed/25071826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00196
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